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Deep brain stimulation was a great success in the treatment of anorexia nervosa

Deep brain stimulation has a good effect on anorexia nervosa. Professor Sun Bomin, director of functional neurosurgery of Ruijin Hospital, announced the results of his two-year postoperative follow-up of more than 20 patients with anorexia nervosa. These patients were ineffective in systematic psychotherapy and drug treatment. Two months after the operation, these patients gained between 17 pounds and 44 pounds, and most patients also had significant improvements in obsessive-compulsive and depressive symptoms.

“Anorexia nervosa is a complex disease involving many factors such as society, neurobiology and psychology.” sun Bomin pointed out that deep brain electrical stimulation is a very effective treatment. Patients’ eating behavior and mental symptoms have been significantly improved after operation. This manual method will become a new alternative treatment.

Sun Bomin and his colleagues performed minimally invasive electrode implantation in 15 patients. The nucleus accumbens (the nerve nucleus of the brain) was stimulated with deep brain electrical stimulation electrodes. The implanted stimulator was the same as the equipment for the treatment of Parkinson’s disease. Among them, 12 patients underwent internal capsule forelimb destruction at the same time of deep brain stimulation implantation. The level of brain metabolism decreased significantly in all patients after operation.

All patients were followed up for 2 to 26 months. The patients who received the combined treatment of lesion and deep brain electrical stimulation had a significant improvement in eating behavior and mental symptoms. The three patients who received deep brain electrical stimulation had a significant improvement in obsessive-compulsive symptoms and anxiety symptoms, and a slight improvement in eating behavior.

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